2023 NCAA Tournament: Sweet 16 Picks & Predictions (Friday)

by BettingPros Staff |
Mar 24, 2023

The Round of 16 is here, and itâ€™s shaping up for a sweet weekend of college basketball. Weâ€™ll have you covered with our best bets throughout the Sweet 16 and Elite 8. Here are our top picks for Fridayâ€™s Sweet 16 action.

Also, take a look at our other best bets for Friday:

Get access to expert NCAA Tournament picks now >>

Sweet 16 Best Bets (2023 NCAA Tournament)

All betting odds are from:

Stop tracking bets manually and get sync your picks for a seamless sport betting experience >>

Alabama vs. San Diego State

Betting against this Alabama juggernaut isnâ€™t fun. However, coach Brian Dutcher is one of the best game planners in the sport, and I think the Aztecs can do enough to slow down the Crimson Tideâ€™s transition offense. Theyâ€™ll probably need a really off shooting night to win outright, but theyâ€™re fully capable of keeping this within the number.

The pick: San Diego State +7.5 (-110)

Houston vs. Miami

On Friday, a Sweet 16 matchup between the No. 1 Houston Cougars (33-3) and the 5-seed Miami Hurricanes (27-7) will tip off in Las Vegas as one team looks to continue its 2023 journey while the other heads home.

The USA TODAY Sports Coaches Poll had Miami at No. 15 in the country to end the regular season, as the Hurricanes went on and defeated Drake and Indiana in the Midwest bracket. With those wins, they have an 11-2 record since Jan. 31 and an 81.4 point per game scoring average over that span.

The Cougars are the top-ranked team in the country and have won their first two tournament games, despite playing with little offensive effectiveness. This was mainly a result of their stellar defense. Houston limited their two opponents to a 32% field goal shooting percentage.

Knocking off a very well-rounded Indiana team on Sunday night, I'm not sure this Miami team is getting the credit it deserves. While Houston continues to struggle offensively, I like for the Hurricanes to keep this one close.

The pick: Miami +7 (-110)

Texas vs. Xavier

The Sweet 16 of the 2022-23 NCAA Tournament begins on Thursday, and on Friday, the 2-seed Texas Longhorns and 3-seed Xavier Musketeers will play in an exciting Midwest Region clash.

On Saturday, Texas defeated No. 10 Penn State 71-66 thanks to a strong first half. In the meantime, Xavier beat No. 11 Pittsburgh 84-73 to make it to the Sweet 16.

Although Xavier's attack has been excellent this season, Texas will prevent them from scoring at will, unlike their opponents have thus far. The Longhorns have kept their last six opponents to a 58.2 PPG average while allowing just 67.2 PPG on the season. Over that time, they totally shut down opponents like TCU and Kansas, demonstrating the Longhorns' ability to handle top opposition.

With the offensive talent present on both sides, I'm anticipating some first-half adjustments to be needed, but I give Texas a much bigger edge. If they can contain Xavier in the first 10 minutes, look for them to settle in, find their shots and pull away late.

The pick: Texas -4 (-110)

Creighton vs. Princeton

This is a really difficult matchup for the Tigers on the offensive end, as the Bluejays can take away Princeton's strengths. Anyone is susceptible to an off night, but I trust Creighton's guards far more than I did Arizona's. Kalkbrenner should be able to get whatever he wants on the interior, and if Princeton doubles him I'd expect McDermott to have his big man prepared to be more of a distributor Friday night.

Princeton's run has been incredible, but this feels like the end of the road.

The pick: Creighton -9.5 (-110)

Get the FREE BettingPros sports betting app and start making winning bets with expert advice and picks >>