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49ers vs. Seahawks: Thursday Night Football Week 15 Odds, Picks & Predictions (2022)

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Let’s take a look at our preview and best bet for the NFL Week 15 game 49ers vs. Seahawks.

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49ers vs. Seahawks: Thursday Night Football Week 15 Odds, Picks & Predictions (2022)

Week 15 kicks off in Seattle, as the Seahawks host the 49ers in a crucial divisional matchup. Seattle has faded of late, dropping three of their last four, and failing to cover in each game. Such disappointment makes them an uneasy bet, but also presents us a great opportunity to back them at a discount.

Seattle’s offense (particularly their passing attack), continues to be one of the best in the NFL, and while their defense has stumbled, they now have the fortune of facing the 49ers absent WR Deebo Samuel and starting QB Jimmy Garroppolo. Further, Lumen Field is one of the most hostile environments in the NFL, and not the ideal place for rookie QB Brock Purdy to make his road start.

Situationally, Seattle has to be the bet. San Fran has been on quite a roll, but there is a degree of uncertainty present with their offense, and this number is too good to pass on.

Seahawks +3.5, Lean u43.5

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