Buccaneers vs. 49ers: NFL Week 14 Odds, Picks & Predictions (2022)

Let’s take a look at our preview and best bet for the NFL Week 14 game Buccaneers vs. 49ers.

And check out our predictions for other Week 14 NFL games:

• Raiders vs. Rams
• Jets vs. Bills
• Browns vs. Bengals
• Texans vs. Cowboys
• Vikings vs. Lions
• Jaguars vs. Titans
• Eagles vs. Giants
• Ravens vs. Steelers
• Chiefs vs. Broncos
• Panthers vs. Seahawks
• Dolphins vs. Chargers
• Patriots vs. Cardinals

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NFL Week 14 Odds, Picks & Predictions: Buccaneers vs. 49ers

Jimmy Garoppolo injured his foot last week against the Dolphins, and he will miss several weeks. Brock Purdy stepped in for Garoppolo and will make his first start this week against the Buccaneers. He was the last pick in the draft and will be facing another quarterback who went off the board as a late-round pick, Tom Brady.

Both teams have a top-five defense regarding points allowed per game. The 49ers are better against the run (75.6 rushing yards per game), while the Buccaneers are better against the pass (195.3 passing yards per game), so the 49ers will likely run the ball more. The Buccaneers have a point differential of -2 this season, and they tend to be in games decided by a field goal. They have 38 sacks as a team this season, so they could get to Purdy early and make it a long day for him.

Lean Buccaneers +3.5, u37.5

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