Buffalo Bills vs. Jacksonville Jaguars Odds & Game Pick (2021)

This AFC match-up features two teams who are on different paths this season. So you have one team looking to play at SoFi Stadium in February, while the other is looking at another top pick in April.

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Details

  • Opening Lines: Bills -13.5; O/U 48.5
  • Current Lines: Bills -14.5; O/U 48.5
  • Location: TIAA Bank Field- Jacksonville, FL
  • Start Time: 1:05 p.m. EDT
  • TV: CBS
  • Last Meeting: November 25, 2018 -  Jaguars 21  at Bills 24

Buffalo is again making a Super Bowl run and looking like the front runners in the AFC. Last week, the Bills struggled early in their matchup with Miami as they were tied three going into halftime, but as a good team does, they re-grouped and pulled away for the 26-11 win. In that game, Josh Allen threw for two touchdowns in the second half, along with a rushing touchdown. Buffalo statistically is the best team in football, as their offense scores the most points in the league, and their defense allows the fewest.

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The Jaguars had their chance for back-to-back wins as they headed to Seattle to face a Seahawks who have played poorly without Russell Wilson. Instead, they came out and were absolute lame ducks. The 27th overall defense made Geno Smith looks like a formable quarterback as he didn't turn the ball for the first time as the Seahawks starting quarterback. In addition, the Jaguars’ offense was being shut out until Trevor Lawrence threw a garbage-time touchdown with under two minutes left in the game. The worse news was their star-sophomore running back James Robinson suffered a bruised heel in the game and has yet to practice this week.

Trends

  • The OVER is 13-7 in Jacksonville’s last 20 games as an underdog vs. AFC teams on Sundays.
  • Buffalo is 10-4-1 against the spread in its last 15 games.
  • Buffalo has won 11 of its last 11 games with an Over/Under between 46.5-50.5, having played the week before.
  • Buffalo has won 19 of its last 25 games vs. AFC teams on Sundays.

This game is an absolute lopsided matchup. With the Bills being number one on both sides of the ball, it does not give the Jaguars any breathing room to stay in this game. This has a great chance of being an absolute disastrous game for Jacksonville, especially if they’re missing their star runner.

Pick: Buffalo -14.5

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