College Football Week 10 Picks & Predictions: James Madison vs. Louisville (2022)
Let’s take a look at the College Football Week 10 odds, picks, and predictions for this week’s game: James Madison vs. Louisville.
And check out our other College Football Week 10 game previews and picks:
- Tennessee vs. Georgia
- Oklahoma State vs. Kansas
- Air Force vs. Army
- Ohio State vs. Northwestern
- Florida vs. Texas A&M
- Alabama vs. LSU
- Clemson vs. Notre Dame
- California vs. USC
- Penn State vs. Indiana
- Arizona vs. Utah
- Illinois vs. Michigan State
- UTSA vs. UAB
- Maryland vs. Wisconsin
- Western Kentucky vs. Charlotte
- UNLV vs. San Diego State
Check out Thor Nystrom's Week 10 College Football Power Rankings >>
College Football Week 10 Odds, Picks & Prediction: James Madison vs. Louisville
James Madison Dukes (-7.5) at Louisville Cardinals, Total 52.5
What a nasty spot for the Cards at home. Louisville is coming off a dominant victory over 10th-ranked Wake Forest and now could be looking ahead to a road clash with Clemson next week. But Louisville can’t look too far ahead, as James Madison is no slouch in its first year in FBS. The 5-2 Dukes are in the running for the competitive Sun Belt, and they actually match up very well with Louisville.
Louisville’s offense is predicated on a ground game that averages 4.94 yards per attempt, which ranks 29th in the country. The problem is the Dukes lead the nation in run defense and are the only team in the country allowing fewer than two yards per carry.
Offensively, James Madison’s 18th-ranked passing game should succeed against a Cardinals secondary giving up 7.5 yards per attempt.
Louisville is susceptible to playing down to its opponents. Considering this letdown and look-ahead spot, I’d take the Dukes at +7 or better.
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