College Football Week 10 Picks & Predictions: Western Kentucky vs. Charlotte (2022)

Let’s take a look at the College Football Week 10 odds, picks, and predictions for this week’s game: Western Kentucky vs. Charlotte.

And check out our other College Football Week 10 game previews and picks:

• Tennessee vs. Georgia
• Oklahoma State vs. Kansas
• Air Force vs. Army
• Ohio State vs. Northwestern
• Florida vs. Texas A&M
• Alabama vs. LSU
• Clemson vs. Notre Dame
• California vs. USC
• Penn State vs. Indiana
• Arizona vs. Utah
• Illinois vs. Michigan State
• UTSA vs. UAB
• James Madison vs. Louisville
• Maryland vs. Wisconsin
• UNLV vs. San Diego State

Check out Thor Nystrom's Week 10 College Football Power Rankings >>

College Football Week 10 Odds, Picks & Prediction: Western Kentucky vs. Charlotte

Bear with me because this pick will raise a few eyebrows. Charlotte has been nothing short of awful this season, which is why their head coach was fired after a 1-7 start and an embarrassing loss to FIU. However, the 49ers responded in week 9 with a throttling of Rice, putting up 514 yards of offense and 8.2 yards per play.

Charlotte brings a defense that is near worst in the country, ranking 130th in defensive SP+. The only way they win any game is with their offense. Western Kentucky is one of those opponents in which they can find themselves in a shootout with. This Charlotte team can go as far as QB Craig Reynolds will take them offensively. If he's on like last week, they can exploit a Western Kentucky defense that ranks only 91st in defensive SP+.

This is the largest moneyline dog we've been on all year, but the way Charlotte responded to a new voice in the clubhouse last week gives me some confidence that the 49ers can force a shootout and pull this off.

Two bad defenses and a home underdog with a capable pass offense is a perfect formula for a longshot upset. I'm going to hold my nose and dive into the Charlotte moneyline.

Pick: Charlotte ML (+460)

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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