College Football Week 2 Odds, Picks & Prediction: Miami vs. Southern Miss (2022)

Let’s take a look at the College Football Week 2 odds, picks, and predictions for this week’s game: Miami vs. Southern Miss.

And check out our other game previews for Week 2:

• Alabama vs. Texas
• USC vs. Stanford
• Baylor vs. BYU
• Kentucky vs. Florida
• Mississippi State vs. Arizona
• Ohio vs. Penn State
• Duke vs. Northwestern
• Boise State vs. New Mexico State
• Maryland vs. Charlotte
• Hawaii vs. Michigan
• Virginia vs. Illinois
• Oregon State vs. Fresno State
• Iowa State vs. Iowa
• UAB vs. Liberty
• Tennessee vs. Pittsburgh
• Ohio State vs. Arkansas State
• Texas Tech vs. Houston
• TCU vs. Tarleton State
• Arizona State vs. Oklahoma State
• Louisville vs. UCF
• UNC vs. Georgia State
• Colorado vs. Air Force
• Houston vs. Texas Tech
• Ohio vs. Penn State
• South Carolina vs. Arkansas
• Notre Dame vs. Marshall
• West Virginia vs. Kansas

Check out Thor Nystrom’s Week 2 College Football Power Rankings >>

College Football Week 2 Early Odds, Picks & Prediction: Miami vs. Southern Miss

The Hurricanes are going to do the heavy lifting to get to the total on this one, and if that hits, the spread should also be a cover. This is simply a gigantic mismatch in Miami’s favor. They put 70 points up last week in another mismatch against FCS Bethune-Cookman. 

Southern Miss is a more formidable opponent, of course, but they looked rough last week. They were particularly bad on defense, where they gave up 244 rushing yards to Liberty and let a 3rd-string QB beat them in OT. They also let Liberty control the clock (38:58-30:55 in 3OT) and had five turnovers and ten penalties. The Golden Eagles might not have starting QB Ty Keyes as well. Even if they aren’t, he probably won’t be at 100%, which will lead to poor field position at best and turnovers at worst.

Miami was crisp in Week 1, has a way better roster, and has a potential NFL-caliber QB in Tyler Van Dyke. I think this is a Miami stomping in all 3 phases and that they will put up the majority (if not all) of this total.

Bet: Miami -24.5 (-110) AND Over 51.5 (-110) on BetMGM

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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