College Football Week 2 Odds, Picks & Prediction: Notre Dame vs. Marshall (2022)

Let’s take a look at the College Football Week 2 odds, picks, and predictions for this week’s game: Notre Dame vs. Marshall.

And check out our other game previews for Week 2:

• Alabama vs. Texas
• USC vs. Stanford
• Baylor vs. BYU
• Kentucky vs. Florida
• Mississippi State vs. Arizona
• Ohio vs. Penn State
• Duke vs. Northwestern
• Boise State vs. New Mexico State
• Maryland vs. Charlotte
• Hawaii vs. Michigan
• Virginia vs. Illinois
• Oregon State vs. Fresno State
• Iowa State vs. Iowa
• UAB vs. Liberty
• Tennessee vs. Pittsburgh
• Ohio State vs. Arkansas State
• Texas Tech vs. Houston
• TCU vs. Tarleton State
• Arizona State vs. Oklahoma State
• Louisville vs. UCF
• UNC vs. Georgia State
• Colorado vs. Air Force
• Houston vs. Texas Tech
• Ohio vs. Penn State
• South Carolina vs. Arkansas

Check out Thor Nystrom’s Week 2 College Football Power Rankings >>

College Football Week 2 Early Odds, Picks & Prediction: Notre Dame vs. Marshall

While Ohio State was the better and more talented team last weekend, what the final score doesn’t indicate is just how long the Fighting Irish hung around. Unlike last week, however, Notre Dame now draws a Marshal team that will allow their young quarterback (Tyler Buchner) to let the ball fly and I think we see that in the game plan out of the gates.

Not much can be drawn from a 55-3 win over Norfolk State last week for Marshall. Their rebuilt defense and offensive line will be tested here vs. the Irish. They’ll also have to now deal with their starting running back being gone for the season.

To me, all signs point towards a Notre Dame route in this one.

Pick: Notre Dame -20

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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