College Football Week 2 Odds, Picks & Prediction: Syracuse vs. UConn (2022)

Let’s take a look at the College Football Week 2 odds, picks, and predictions for this week’s game: Syracuse vs. UConn.

And check out our other game previews for Week 2:

• Alabama vs. Texas
• USC vs. Stanford
• Baylor vs. BYU
• Kentucky vs. Florida
• Mississippi State vs. Arizona
• Ohio vs. Penn State
• Duke vs. Northwestern
• Maryland vs. Charlotte
• Hawaii vs. Michigan
• Virginia vs. Illinois
• Oregon State vs. Fresno State
• UAB vs. Liberty
• Tennessee vs. Pittsburgh
• Ohio State vs. Arkansas State
• Texas Tech vs. Houston
• TCU vs. Tarleton State
• Arizona State vs. Oklahoma State
• UNC vs. Georgia State
• Colorado vs. Air Force
• Houston vs. Texas Tech
• Ohio vs. Penn State
• South Carolina vs. Arkansas
• Notre Dame vs. Marshall
• Miami vs. Southern Miss

Check out Thor Nystrom’s Week 2 College Football Power Rankings >>

College Football Week 2 Odds, Picks & Prediction: Syracuse vs. UConn

The Orange were one of the pleasant surprises of Week 1, blasting Louisville 31-7. It appears Syracuse's passing game and defense have both taken a large step forward since the end of last season. The offense is now directed by respected OC Robert Anae, who appears to have coaxed major improvement out of the passing attack with his quick-hitting sideline-to-sideline machinations.

That performance should have gotten Syracuse upgraded in power rankings. But the sportsbooks appear to have overlooked that, dropping a spread more indicative of the preseason outlooks for both teams.

I purchased a Syracuse +20.5 ticket on Sunday. Since then, predictable money on the Orange has come in to push this spread to -22.5. I still think there's value on Syracuse at this number - I would bet them up to -24.

Bet: Syracuse (-22.5)

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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