College Football Week 3 Odds, Picks & Prediction: Mississippi State vs. LSU (2022)

Let’s take a look at the College Football Week 3 odds, picks, and predictions for this week’s game: Mississippi State vs. LSU.

• Texas vs. UTSA
• Rutgers at Temple
• Ohio State vs. Toledo
• Kentucky vs. Youngstown State
• UCLA vs. South Alabama
• Notre Dame vs. California
• Kansas State vs. Tulane
• UNLV vs. North Texas
• Washington vs. Michigan State
• Texas A&M vs. Miami
• Western Kentucky at Indiana
• New Mexico State at Wisconsin
• Marshall at Bowling Green
• Charlotte at Georgia State
• Oklahoma at Nebraska
• Florida State vs. Louisville
• Air Force vs. Wyoming
• Georgia v. South Carolina
• UConn v. Michigan
• Washington State vs. Colorado State
• BYU vs. Oregon
• Ole Miss vs. Georgia Tech
• Penn State vs. Auburn
• Fresno State vs. USC

Check out Thor Nystrom’s Week 3 College Football Power Rankings >>

College Football Week 3 Early Odds, Picks & Prediction: Mississippi State vs. LSU

The Bulldogs will head south on Saturday to take on LSU team who is very much still in the SEC picture moving forward from a week one loss vs. FSU. Routing Southern 65-17 and covering as 44.5-point favorites on Saturday, LSU will now turn to their SEC schedule as it ramps up over the coming month; beginning with Mississippi State.

For the Bulldogs, QB Will Rogers is already vying to be an early Heisman darkhorse, leading the country in completed passes and currently tied for #2 with nine touchdown passes. His 381.5 passing yards per game also rank in the top five in the country.

As for LSU, Jayden Daniels has been what many Tigers fans expected, becoming the first QB in LSU history to pass for 200 and run for 100 yards in a game. LSU should also get a boost this week from the return of running back John Emery, his first appearance this season.

Pick: LSU +2.5

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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