College Football Week 3 Odds, Picks & Prediction: Oklahoma at Nebraska (2022)

Let’s take a look at the College Football Week 3 odds, picks, and predictions for this week’s game: Oklahoma at Nebraska.

And check out our other Week 3 College Football Game Previews & Picks:

• Fresno State vs. USC
• Mississippi State vs. LSU
• Penn State vs. Auburn
• Ole Miss vs. Georgia Tech
• BYU vs. Oregon
• Washington State vs. Colorado State
• UConn vs. Michigan
• Georgia vs. South Carolina
• Charlotte at Georgia State
• Notre Dame vs. California
• New Mexico vs. UTEP
• Houston vs Kansas
• Texas vs UTSA
• Marshall at Bowling Green
• New Mexico State at Wisconsin
• Western Kentucky at Indiana
• Toledo at Ohio State
• Tulane at Kansas State
• Miami at Texas A&M

Check out Thor Nystrom’s Week 3 College Football Power Rankings >>

College Football Week 3 Early Odds, Picks & Prediction: Oklahoma at Nebraska

Following another thrilling loss, the Scott Frost era at Nebraska is finally over. It seemed that no matter how well things would go during the game they could never manage to get out of their own way, regardless of the opponent. As they hope to turn a new leaf in Lincoln, long-time rival Oklahoma comes to town. Oklahoma has looked impressive in wins over UTEP and Kent State, but we don't know what to expect from the Sooners as these opponents both rank in the bottom 20 in SP+ ratings.

Texas transfer Casey Thompson will look to repeat his performance from his matchup with Oklahoma last year where he had a career-best 388 passing yards along with five touchdowns and zero interceptions. This team has the ability to move the ball and Oklahoma has yet to see an offense with this caliber of athleticism. This is a team that has hung with top 10 opponents regularly the last two seasons, including a one-possession loss in Norman last year. With Frost now out of the picture, perhaps Nebraska can finally exercise the demons that have plagued this program. The talent on these two rosters is closer than the spread would indicate and Nebraska's offense should be able to keep them in this until the end.

Pick: Nebraska ML (+335)

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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