College Football Week 3 Odds, Picks & Prediction: Western Kentucky at Indiana (2022)

Let’s take a look at the College Football Week 3 odds, picks, and predictions for this week’s game: Western Kentucky at Indiana.

And check out our other Week 3 College Football Game Previews & Picks:

• Fresno State vs. USC
• Mississippi State vs. LSU
• Penn State vs. Auburn
• Ole Miss vs. Georgia Tech
• BYU vs. Oregon
• Washington State vs. Colorado State
• UConn vs. Michigan
• Georgia vs. South Carolina
• Oklahoma at Nebraska
• Charlotte at Georgia State
• Notre Dame vs. California
• New Mexico vs. UTEP
• Houston vs Kansas
• Texas vs UTSA
• Marshall at Bowling Green
• New Mexico State at Wisconsin
• Toledo at Ohio State
• Tulane at Kansas State
• Miami at Texas A&M

Check out Thor Nystrom’s Week 3 College Football Power Rankings >>

College Football Week 3 Early Odds, Picks & Prediction: Western Kentucky at Indiana

You may remember the Hilltoppers as one of college football’s emerging teams from a season ago, as a high-powered passing game led by Bailey Zappe went 9-5 in 2021. Zappe is gone, but the 2-0 Hilltoppers still have a top-50 passing game nationally.

Western Kentucky will face its toughest test of the young season when they travel to Bloomington for a battle with the Hoosiers, who have struggled out of the gates. Despite a 2-0 record, things haven’t been pretty for IU. The Hoosiers won in Week 1 thanks to a late-game meltdown from Illinois. Last week, they trailed 10-0 to Idaho before rallying in the second half.

Indiana is a transfer-laden team that still seems to be getting its footing. Missouri transfer QB Connor Bazelak hasn’t been great, and neither has a pass defense that ranks 106th in the country in coverage, per Pro Football Focus.

Austin Reed, who transferred in from West Florida this offseason, now leads Western Kentucky. He’s so far been a good fit in coach Tyson Helton’s offense, and he should be able to move the ball against a lackluster Hoosiers defense.

I pounced on the opening number of Western Kentucky +9, but even at +6.5, this line has value.

The pick: Western Kentucky +6.5

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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