College Football Week 4 Odds, Picks & Prediction: Florida vs. Tennessee (2022)

Let’s take a look at the College Football Week 4 odds, picks, and predictions for this week’s game: Florida vs. Tennessee.

And check out our other College Football Week 4 game previews and best bets:

• Indiana vs. Cincinnati
• Kentucky vs. Northern Illinois
• Western Kentucky vs. FIU
• Washington vs. Stanford
• Kansas vs. Duke
• Purdue vs. Florida Atlantic
• Boston College vs. Florida State
• Charlotte vs. South Carolina
• Old Dominion vs. Arkansas State
• Central Michigan vs. Penn State
• TCU vs. SMU
• Notre Dame vs. UNC
• Arizona vs. California
• Clemson vs. Wake Forest
• James Madison vs. Appalachian State
• USC vs. Oregon State
• Missouri vs. Auburn
• Maryland vs. Michigan
• Arkansas vs. Texas A&M
• Wisconsin vs. Ohio State
• Kansas State vs. Oklahoma

Check out Thor Nystrom’s Week 4 College Football Power Rankings >>

College Football Week 4 Odds, Picks & Prediction: Florida vs. Tennessee

It's been more than 30 years since we saw a spread this big in the Florida vs. Tennessee rivalry, but here we are as the Volunteers are laying 10.5 points as kickoff approaches. For Florida, an opening game win over the highly touted Utah was quickly forgotten after they laid a dud the following week losing to Kentucky at home 16-26. The season was almost over last week, needing the final minutes to beat a USF team at home by three as 23-point favorites.

For the Volunteers, optimism is at the highest levels it’s been in more than 10 years, as they come into this game 3-0 (3-0 ATS) with a win at Pittsburgh their most impressive to date. The QB-WR combination of Henden Hooker and Jalin Hyatt is slowly morphing into one of the best in the SEC, as the duo racked up a career-high 166 yards in their last game.

While all signs on paper point towards the Volunteers in this one, especially in a revenge spot from Florida's 38-14 win last season, I smell something fishy. I think the Gators have enough to keep this one close.

Pick: Florida +10.5

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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