College Football Week 4 Odds, Picks & Prediction: Indiana vs. Cincinnati (2022)

Let’s take a look at the College Football Week 4 odds, picks, and predictions for this week’s game: Indiana vs. Cincinnati.

And check out our other College Football Week 4 game previews and best bets:

• Kentucky vs. Northern Illinois
• Western Kentucky vs. FIU
• Washington vs. Stanford
• Kansas vs. Duke
• Purdue vs. Florida Atlantic
• Boston College vs. Florida State
• Charlotte vs. South Carolina
• Old Dominion vs. Arkansas State
• Central Michigan vs. Penn State
• TCU vs. SMU
• Notre Dame vs. UNC
• Arizona vs. California
• Clemson vs. Wake Forest
• James Madison vs. Appalachian State
• USC vs. Oregon State
• Missouri vs. Auburn
• Maryland vs. Michigan
• Florida vs. Tennessee
• Arkansas vs. Texas A&M
• Wisconsin vs. Ohio State
• Kansas State vs. Oklahoma

Check out Thor Nystrom’s Week 4 College Football Power Rankings >>

College Football Week 4 Odds, Picks & Prediction: Indiana vs. Cincinnati

Indiana Hoosiers at Cincinnati Bearcats -17, Total 56.5

Kickoff: Saturday, 3:30 ET

We faded the Hoosiers last week, and it worked, as Indiana needed overtime to beat Western Kentucky last week.

Now Indiana travels to Cincinnati for a rematch with the Bearcats. The Hoosiers have been significantly out-gained in two of their three games against Illinois and Western Kentucky. And IU was losing 10-0 to Idaho at halftime a couple of weeks ago.

The Connor Bazelak experiment hasn’t fared very well, as the Missouri transfer QB has completed just 56% of his passes for five touchdowns and two interceptions. Again, this is against Illinois, Idaho and Western Kentucky. And Bazelak’s struggles could continue against a Bearcats defense allowing 150 passing yards per game.

Offensively, the Bearcats also hold a considerable advantage. Quarterback Ben Bryant has done a good job replacing Desmond Ridder, throwing for 863 yards, seven touchdowns and two picks while completing 70% of his throws. The Bearcats rank 16th nationally in passing offense, while Indiana ranks 93rd against the pass.

This isn’t last year’s Cincinnati team. But it gave a strong Arkansas team everything it could handle on the road. The Bearcats should roll.

The pick: Cincinnati -17 (-110)

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