College Football Week 4 Odds, Picks & Prediction: Notre Dame vs. UNC (2022)

Let’s take a look at the College Football Week 4 odds, picks, and predictions for this week’s game: Notre Dame vs. UNC.

And check out our other College Football Week 4 game previews and best bets:

• Indiana vs. Cincinnati
• Kentucky vs. Northern Illinois
• Western Kentucky vs. FIU
• Washington vs. Stanford
• Kansas vs. Duke
• Purdue vs. Florida Atlantic
• Boston College vs. Florida State
• Charlotte vs. South Carolina
• Old Dominion vs. Arkansas State
• Central Michigan vs. Penn State
• TCU vs. SMU
• Arizona vs. California
• Clemson vs. Wake Forest
• James Madison vs. Appalachian State
• USC vs. Oregon State
• Missouri vs. Auburn
• Maryland vs. Michigan
• Florida vs. Tennessee
• Arkansas vs. Texas A&M
• Wisconsin vs. Ohio State
• Kansas State vs. Oklahoma

Check out Thor Nystrom’s Week 4 College Football Power Rankings >>

College Football Week 4 Odds, Picks & Prediction: Notre Dame vs. UNC

Notre Dame Fighting Irish at North Carolina Tar Heels -2, Total 56.5

Kickoff: Saturday, 3:30 ET

This is a true strength-on-strength and weakness-on-weakness battle. The Tar Heels boast the sixth-highest scoring offense in the nation at 51.7 points per game. The Fighting Irish have been stout defensively, allowing just 21.3 points per game.

On the other side, Notre Dame’s offense has struggled mightily this year, averaging just 18.3 points per game and ranking outside the top 100 in both rushing and passing offense. The Tar Heels can’t stop a nosebleed, however. UNC is giving up 37.7 points per game against three non-Power Five conference foes, ranking 111th and 112th in rushing and passing offense, respectively.

The key to this game will be whether Notre Dame quarterback Drew Pyne can take advantage of North Carolina’s generous defense. Since taking over for Tyler Buchner two weeks ago against Marshall, Pyne has completed 69% of his passes for 170 yards, three touchdowns and an interception. Pyne’s been the steadier passer, but he doesn’t offer the same rushing upside as Buchner.

Tar Heels quarterback Drake Maye could be the next up-and-coming quarterback, as the freshman has completed 74% of his throws for 930 yards, 11 touchdowns and only one pick. The Irish secondary will be the toughest test of his young career. However, UNC’s 13th-ranked rushing offense should find room to run against an Irish front seven, yielding 167 yards per game on the ground.

North Carolina is coming off a bye, while Notre Dame had to survive against Cal last week. I’m willing to bet on North Carolina’s defense getting more stops against this weak Irish offense led by Pyne.

The pick: North Carolina Moneyline (-125)

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