College Football Week 5 Odds Pick & Prediction: Michigan State vs. Maryland (2022)

Let’s take a look at the College Football Week 5 odds, picks, and predictions for this week’s game: Michigan State vs. Maryland.

Check out our other best college football bets for Week 5:

• Tulane vs. Houston
• San Diego State vs. Boise State
• Washington vs. UCLA
• Alabama vs. Arkansas
• Michigan vs. Iowa
• Kentucky vs. Ole Miss
• LSU vs. Auburn
• Arizona State vs. USC
• NC State vs. Clemson
• Oklahoma State vs. Baylor
• Oklahoma vs. TCU
• UTSA vs. Middle Tennessee State
• Northwestern vs. Penn State
• Colorado vs. Arizona
• Georgia Southern vs. Coastal Carolina
• UL Monroe vs. Arkansas State
• Florida State vs. Wake Forest
• East Carolina vs. South Florida
• Texas State vs. James Madison
• Texas vs. West Virginia
• Rutgers vs. Ohio State
• Old Dominion vs. Liberty
• New Mexico State vs. FIU

Check out Thor Nystrom’s Week 5 College Football Power Rankings >>

College Football Week 5 Early Odds, Picks & Prediction: Michigan State vs. Maryland

Michigan State Spartans at Maryland Terrapins (-7.5) | Total 60.5

Kickoff: Saturday, 3:30 ET

Maybe I’m just chasing my own tail with Michigan State. But once again, this feels like a buy-low spot on a Spartans program that I’m not giving up on.

The Spartans have struggled mightily to sustain drives and move the ball in losses to Washington and Minnesota. But both of those programs possess strong defenses. Maryland isn’t exactly a defensive powerhouse, ranking 78th against the run and 98th against the pass.

Plus, Maryland QB Taulia Tagovailoa and leading receiver Rakim Jarrett are both game-time decisions due to injuries. I repeat: This isn’t pretty. But I’d expect maximum effort from a Spartans team looking to save its season.

The pick: Michigan State +7.5 (-105 on FanDuel)

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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