College Football Week 5 Odds Pick & Prediction: UTSA vs. Middle Tennessee State (2022)

Let’s take a look at the College Football Week 5 odds, picks, and predictions for this week’s game: UTSA vs. Middle Tennessee State.

Check out our other best college football bets for Week 5:

• Tulane vs. Houston
• San Diego State vs. Boise State
• Washington vs. UCLA
• Alabama vs. Arkansas
• Michigan vs. Iowa
• Kentucky vs. Ole Miss
• LSU vs. Auburn
• Arizona State vs. USC
• NC State vs. Clemson
• Oklahoma State vs. Baylor
• Oklahoma vs. TCU
• Michigan State vs. Maryland
• Northwestern vs. Penn State
• Colorado vs. Arizona
• Georgia Southern vs. Coastal Carolina
• UL Monroe vs. Arkansas State
• Florida State vs. Wake Forest
• East Carolina vs. South Florida
• Texas State vs. James Madison
• Texas vs. West Virginia
• Rutgers vs. Ohio State
• Old Dominion vs. Liberty
• New Mexico State vs. FIU

Check out Thor Nystrom’s Week 5 College Football Power Rankings >>

College Football Week 5 Early Odds, Picks & Prediction: UTSA vs. Middle Tennessee State

UT-San Antonio Roadrunners (-4) at Middle Tennessee State Blue Raiders | Total 63

Kickoff: Friday, 7:30 ET

We start by fading one of the biggest surprise stories from Week 4. Did you know Middle Tennessee State walked into Miami and beat the Hurricanes by two touchdowns? It was an impressive win, no doubt. But it also sets up an enormous letdown spot for the Blue Raiders, who have probably been riding high since Saturday.

Led by quarterback Frank Harris, the Roadrunners possess one of the most high-powered passing games in the country. UTSA ranks sixth in the nation with an average of 351.5 passing yards per game. The Roadrunners should throw all over a Middle Tennessee secondary that ranks 89th in pass defense.

Middle Tennessee’s top 25 run defense won’t be as big of a factor in this matchup. Their best shot in this game will be to find success on the ground against a Roadrunners defense that ranks 122nd against the run. The problem is the Blue Raiders have averaged just 112 rushing yards per game this year, which ranks 110th.

UTSA has also played a stronger schedule, facing Houston, Army, and Texas this season. In contrast, the Blue Raiders have beaten Tennessee State and a miserable Colorado State in addition to Miami.

Take this opportunity to get the better Roadrunners at a cheaper price.

The pick: UTSA -4.5, play to -6 (-110 on FanDuel)

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

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