Eagles vs. Cowboys: NFL Week 16 Odds, Picks & Predictions (2022)

Let’s take a look at our preview and best bet for the NFL Week 16 game Eagles vs. Cowboys.

And check out our predictions for other Week 16 NFL games:

• Bills vs. Bears
• Saints vs. Browns
• Texans vs. Titans
• Seahawks vs. Chiefs
• Giants vs. Vikings
• Bengals vs. Patriots
• Lions vs. Panthers
• Falcons vs. Ravens
• Commanders vs. 49ers
• Raiders vs. Steelers
• Packers vs. Dolphins
• Broncos vs. Rams
• Buccaneers vs. Cardinals
• Chargers vs. Colts

View our Pick of the Day in the BettingPros mobile app (free!) >>

NFL Week 16 Odds, Picks & Predictions: Eagles vs. Cowboys

These teams faced each other in week six, and the Eagles prevailed 26 to 17. The Eagles forced three turnovers against the Cooper Rush-led Cowboys, but both teams will likely have a different quarterback this time. Jalen Hurts has not practiced this week due to a shoulder injury, and Gardner Minshew is taking first-team reps. The Eagles are one win away from clinching home-field advantage and a bye in the playoffs, so they may rest Hurts to allow him time to heal. Minshew has played little minutes this season, but the Cowboys’ defense is weak against the run (133.1 yards per game).

The Eagles have forced the most turnovers this season (24) and allow the sixth-fewest points. Dak Prescott has a 17 to 11 TD-to-interception ratio in nine starts this season. This unit should be able to keep them in the game even with Minshew behind center.

Lean Eagles +5, u47.5

---

Whether you're new to sports betting or a betting pro, our Sports Betting Strategy and Advice page is for you. You can get started with our 101 section - including 10 Sports Betting Tips for Beginners - or head to more advanced strategies - like Key Numbers When Betting Against the Spread - to learn more.

View 5-star bets and historical prop performance by player with our Prop Bet Analyzer >>

Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | RadioPublic | Breaker | Castbox | Pocket Casts