Jaguars vs. Colts: NFL Week 1 Odds & Picks (2023)

Sunday marks the first full slate of NFL games for the 2023 season. Make sure to check in with BettingPros throughout the year for top picks and predictions for each and every NFL game. Our writers dive into their favorite picks and predictions for every remaining game on this weekend’s NFL slate. And let’s take a closer look at Jaguars vs. Colts.

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NFL Week 1 Odds, Picks & Predictions: Jaguars vs. Colts

Jaguars vs. Colts

Big expectations for the Jaguars coming into this season as they won their first AFC South title since 2017. Quarterback Trevor Lawrence saw significant improvements in his sophomore season, especially with his passing efficiency and minimizing interceptions. His receiving core got a massive upgrade, with the addition of former Falcon Calvin Ridley returning after being suspended last year for sports betting. The Colts are starting fresh with their fourth different opening week quarterback in four years, along with a rookie head coach. Anthony Richardson was a highly touted prospect coming out of Florida and is equipped with a strong arm and ability to move outside of the pocket. He'll try to do it without the anchor of a strong running back, as Jonathan Taylor will not be suiting for the team anytime soon. Jacksonville has the complete package with running back depth, excellent receivers, and a defense that was sixth in turnovers last year and will come out with a defiant win against a rebuilding team.

Pick: Jaguars -4.5 (-110)


What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.


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