NFL Divisional Round: Favorite Bets (2025)

The NFL playoffs are well underway, and the stakes couldn't be higher! As the Divisional Round kicks off, we've gathered insights from our Featured Pros to bring you the top bets for this week's matchups, offering bold predictions and valuable betting insights for the postseason. Let's dive into the best bets and bold calls for the 2025 playoffs!

Divisional Round: Favorite Bets

What is your favorite Game Pick or Prop Bet for the Divisional Round of the NFL Playoffs and why?

“I get all the reasons why you shouldn’t bet the over on the total in the Ravens-Bills game — 51.5 is a big number, Lamar has a questionable history in the playoffs, the Ravens blew out the Bills earlier this season — it all makes sense. And yet, I can’t help but think this is going well over. The two best QBs in football this season are Hall of Fame talents at the peak of their powers. Derrick Henry in cold weather. Defenses that have struggled at various times this season trying to stop exactly what the opposing offense wants to do. Maybe it’s a sucker’s bet, maybe it’s just because it would be fun to see, I don’t care. I’m taking the Over in Ravens-Bills, and I’m enjoying every touchdown Sunday night.”
– Ryan Wormeli (FantasyPros)

“Derrick Henry is all but a lock to have over 99.5 rushing yards on Sunday night against the Buffalo Bills (-120 on BetMGM). The superstar finished second in the NFL with 1,921 rushing yards during the regular season, the second-highest total of his career. More importantly, he averaged 113 rushing yards per game during the regular season, totaling 106 or more in 53.9% of the contest, including a season-high 199 in the Week 4 matchup against the Buffalo Bills. The future Hall of Famer had 186 rushing yards and a 7.2 yards per attempt average in the win over the Pittsburgh Steelers last week. I would bet the over on Henry's rushing yards on an alternative line up to 150, especially with the expected weather conditions in Buffalo.”
– Mike Fanelli (FantasyPros)

“Jahmyr Gibbs Over 84.5 Rushing Yards (-115 BetMGM) Gibbs has rushed for 100 yards in three consecutive games, and even though David Montgomery is expected to suit up on Saturday, Gibbs will still be the primary back in Detroit for this game. Gibbs has proven that he can shoulder the load for the Lions, and in a game that the Lions should be winning against a defense that allowed over 135 rushing yards per game this season, I expect him to dominate yet again. Montgomery will steal some carries, but the Lions are thinking Super Bowl. If Gibbs has success early, expect the Lions to continue to use him while they ease Montgomery back in.”
– Phil Wood (Bet On Phil Wood)

“James Cook UNDER 55.5 rushing yards (-110 DraftKings) Two RBs this season have surpassed 55.5 rushing yards (Saquon Barkley, Najee Harris) against the Ravens' stout run defense. Cook was limited to 39 rushing yards versus the Ravens back in Week 4. Also, according to Next Gen Stats, Cook has run to the weak side of the formation on 54.6% of his carries this season, which is the highest rate in the NFL (min. 150 total carries). He averaged 1.7 yards before contact per carry on runs directed to the weak side compared to just 1.0 yards before contact per carry on runs directed to the strong side of the formation. But the Ravens defense allowed the fourth-fewest yards per carry (3.6) and a league-low 28.2% success rate on carries directed to the weak side by opposing running backs this season, the 2nd-lowest success rate allowed by any defense over the past six seasons (since 2019).”
– Andrew Erickson (FantasyPros)

“John Metchie under 36.5 receiving yards. Metchie has topped this number in only two of the 14 games he's played this season. He had 28 receiving yards last week vs. the Chargers, even though he tied a season-high with eight targets. Matchie played only 51% of the Texans' offensive snaps last week. For his career, Matchie has averaged only 6.1 yards per target and 1.01 yards per route run. Look for Chiefs defensive coordinator Steve Spagnuolo and the Kansas City D to snuff out the Houston passing game this week. ”
– Pat Fitzmaurice (FantasyPros)

“Philadelphia Eagles (-6) vs. L.A. Rams: I would never describe any of my picks (or anyone else’s, for that matter) to be “locks,” especially with the unpredictable nature of the NFL. That said, I like Philadelphia at home to cover against the Rams. When they played earlier this year in Los Angeles, the Eagles dominated. I think they’re too tough in the trenches for L.A. and should control the line of scrimmage. As long as Jalen Hurts stays healthy, the Eagles will be a tough out, imo.”
– Mark Ringo (Sleepers and Busts)

“We are running it back with Dalton Schultz this week and his anytime touchdown prop (+475 BetMGM). The last time he played Kansas City, he got into the end zone with only his second receiving touchdown of the season. I love his chances of getting into the end zone again this week. Schultz has seen six red zone targets in his last eight games. C.J. Stroud needs a second option in the passing game to step up this week, opposite Nico Collins, and Schultz should be that guy.”
– Derek Brown (FantasyPros)