NFL Monday Night Football Odds, Picks & Predictions: 49ers vs Cardinals (Week 11)

We’re here to guide you through another week of NFL sports betting. Let’s take a look at our picks and predictions for Week 11’s game between the 49ers vs Cardinals.

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NFL Week 11 Odds, Picks & Predictions: 49ers vs Cardinals

The Cardinals come off a convincing win against the Stafford-less Rams and host the 49ers in hopes of keeping their divisionsal chances alive.

The Cardinals defense has been their kryptonite allowing a third-worst 25.8 points per game. Compared to the 49ers who sit fourth at 18.1, there is a huge discrepancy between these teams. The 49ers are clear favorites in this game statistically, but are they really 8 points better than the Cardinals?

Arizona has consistently won the turnover battle this season giving the ball away less than once per game while the 49ers average 1.4 giveaways per game. Obviously Kyler Murray has a lot to do with where this spread will end up, but given Murray starting under center, take the 8 points at home in primetime and run.

Cardinals +8, Lean o43.5

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