NFL Sunday Night Football Picks & Predictions: Chargers vs 49ers (Week 10)
Let’s take a look at our favorite odds, picks, and predictions for the Week 10 NFL game Chargers vs 49ers.
And check out the rest of our Week 10 NFL picks and predictions:
- Seahawks vs Buccaneers
- Broncos vs Titans
- Browns vs Dolphins
- Saints vs Steelers
- Lions vs Bears
- Vikings vs Bills
- Texans vs Giants
- Jaguars vs Chiefs
- Colts vs Raiders
- Cowboys vs Packers
- Cardinals vs Rams
- Commanders vs Eagles
(Odds via FanDuel Sportsbook)
NFL Week 10 Odds, Picks & Predictions: Chargers vs 49ers
The 49ers have historically struggled in this spot under HC Kyle Shanahan. As a home favorite, the Niners are 8-17-1 ATS since Shanahan took control in 2017. Further, the line itself feels egregious. The 4-4 Niners lack a signature win on the season, and for them to be a seven point favorite is shocking. The appeal of the 49ers is obvious, but the team has yet to reach its full potential, and it is unwise to buy them at a premium Sunday Night. Additionally, this has been a good spot for the Chargers. LA is 7-3 ATS as a road underdog in Justin Herbert starts, and are a perfect 4-0 ATS on the road this season.
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