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NFL Week 1 Odds, Picks & Predictions: Saints vs. Falcons (2022)

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Here is our preview and best bet for the 2022 NFL Week 1 game between the Saints vs. Falcons.

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NFL Week 1 Odds, Picks & Predictions: Saints vs. Falcons

In their first game absent former HC Sean Payton, the New Orleans Saints visit the Atlanta Falcons in an NFC South battle. Even amid a regime change, many are bullish on the Saints’ outlook in 2022. The Saints will return both QB Jameis Winston and All-Pro WR Michael Thomas from injury, and much of their elite defense remains intact.

After shipping franchise icon Matt Ryan to Indianapolis this past March, the Falcons also represent a team in a transition. Atlanta, however, seems intent on building for the future rather than competing this season.

Both the expectations and the talent disparity between these NFC South rivals are drastically different. Expect the Saints to build upon last season's early success with Jameis Winston under center in Week 1.

Picks: Lean Saints -5.5 | o42.5


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