NFL Week 1 Odds, Picks & Predictions: Colts vs. Texans (2022)

Here is our preview and best bet for the 2022 NFL Week 1 game between the Colts vs. Texans.

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NFL Week 1 Odds, Picks & Predictions: Colts vs. Texans

Davis Mills will start at quarterback for the Texans this season and will not have much around him again. Dameon Pierce, who the team drafted in the sixth round out of Florida, will start at running back and may add a spark to the offense.

Matt Ryan will be making his Colts debut, and he may not have to do much. The Texans gave up the second most yards and touchdowns last season against the run. The Colts have an elite offensive line and an elite running back in Jonathan Taylor. He feasted on the Texans' defense last year, posting 145 yards and two TDs in their first matchup. He followed that up with 143 yards and two more TDs in their next meeting. The Colts won those games 31-3 and 31-0. This year should not look that much different with Ryan under center.

Picks: Lean Colts -7.5 | u46


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