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NFL Week 1 Odds, Picks & Predictions: Jaguars vs. Commanders (2022)

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Here is our preview and best bet for the 2022 NFL Week 1 game between the Jaguars vs. Commanders.

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NFL Week 1 Odds, Picks & Predictions: Jaguars vs. Commanders

After a nightmare 2021 campaign, the Jaguars are looking for a fresh start with Doug Pederson as head coach. Pederson has a reputation of being a quarterback whisperer from helping Alex Smith revive his career in Kansas City and allowing Nick Foles to turn into a Super Bowl winner. Trevor Lawrence, under Pederson’s tutelage, has all the talent in the world to take his game to the next level, and the Washington pass defense that disappointed in 2021 is a matchup he can exploit. This Jaguars offense will surprise a lot of people, starting in Week 1.

Meanwhile, the Commanders, with Carson Wentz at quarterback, won't be able to keep pace even against a weak defense. Last year in Indianapolis, Wentz struggled in both matchups with the Jaguars, and there's no reason to think that changes enough on Sunday to put them over the top.

Bets: Jaguars +3 | o43.5


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