NFL Week 1 Odds, Picks & Predictions: Saints vs. Falcons (2022)

Here is our preview and best bet for the 2022 NFL Week 1 game between the Saints vs. Falcons.

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NFL Week 1 Odds, Picks & Predictions: Saints vs. Falcons

As the Saints begin their first year without Sean Payton since 2005, some old faces could help them compete this season.

Jameis Winston will return at quarterback, coming off a torn ACL in Week 8 last season. They will also see the return of Michael Thomas as he has not seen the field since Week 14 of 2020 and has dealt with injuries for the past two years.

The running game will feature the two-headed monster of Alvin Kamara and Mark Ingram, and this looks like they're strong on the ground and the air.

The Falcons will field what feels like a brand new team. Matt Ryan and the entire starting wide receivers are gone, and they will feature a new set of skilled players.

They brought in former Raiders backup Marcus Mariotta as the quarterback. They drafted former USC standout Drake London in the first round to provide another large target along with Kyle Pitts.

The running game will see the return of Cordarrelle Patterson, but they've revamped a whole new depth chart, including drafting Tyler Allgeier and signing Damien Willams.

The big question is, how will the defense be this year? They will have as many as seven new starters on a defense that finished 26th in points allowed.

New Orleans has both the offensive and defensive advantage in this game, and it will take some time before for the new Falcons team to gel.

Bet: Saints -5.5


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