NFL Week 11 Early Odds, Picks & Predictions: 49ers vs. Cardinals (2022)

I provide early lines of note and expected movement for Week 11 as we explore ways to capitalize on odds ahead of the weekend. And let’s take a deeper look at the Week 11 NFL game 49ers vs. Cardinals.

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NFL Week 11 Early Odds, Picks & Predictions: 49ers vs. Cardinals

The 49ers have won two in a row to get back above .500. However, in their last four games, they are just 1-3 against the spread, and they failed to cover at home as 7.5-point favorites on Sunday night.

The Cardinals took care of business against the Rams even though Kyler Murray was out with a hamstring injury. Yet, bettors do not seem impressed since the win came with Matthew Stafford out. Before that game, the Cardinals had lost four of their previous five.

This line seems like it was made assuming that Murray will be out again this week. However, even if he is, Colt McCoy was solid in the Cardinals’ win, completing 26 of 37 passes for 238 yards and one touchdown. Therefore, no matter who is under the center, look for this line to drop below the key number.

Current Line: 49ers -7.5

Predicted Final Line: 49ers -6.5

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