NFL Week 12 Odds, Picks & Predictions: Chargers vs Cardinals (2022)

Thanksgiving is in the rearview, but there is still plenty of NFL action for Week 12. Let’s take a look at our preview and best bet for the NFL Week 12 game Chargers vs Cardinals.

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NFL Week 12 Odds, Picks & Predictions: Chargers vs Cardinals

Both the Chargers and the Cardinals are bottom 4 in points allowed and both have been struggling overall to stop offenses from doing what they want. The Chiefs put up 485 yards versus the Chargers last week and the Cardinal's defense looked like they had given up by the end of the Monday night beat down versus San Fransisco. For both of these teams, this game feels like a must-win to keep their playoff chances alive.

Expect to see points. Especially if Kyler Murray is back in the lineup this Sunday, expect to see a barn-burner atmosphere where both teams desperately need to win. A game-winning field goal is all that will separate these teams in the end.

Lean Cardinals +3, o48

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