NFL Week 2 Odds, Picks & Predictions (2024)

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NFL Week 2 Odds, Picks & Predictions

Saints vs. Cowboys

New Orleans looked phenomenal last week; Derek Carr couldn't miss, the run game was unstoppable, and the defense was relentless. They were the high scorers in Week 1 with 47 points. Dallas struggled to run the ball, Dak Prescott managed the game well, and the offense scored 33 points. But it had a ton of help from the defense, who kept giving the offense excellent field position. However, you have to remember that the Saints played a dreadful Carolina team, while Dallas faced last season's No. 1 defense. New Orleans will have to work a lot harder to get the offense on track in this game. Dallas shouldn't find it as challenging to do so against the Saints defense. If Dak can play another mistake-free game, the Cowboys should easily win this one.

Pick: Dallas -6

  • Travis Pulver

Buccaneers vs. Lions

The schedule makers had some fun with the early season schedule for Detroit. In Week 1, they got a Playoff rematch with the Rams, and in Week 2, they’ll get another one with the Buccaneers. Tampa looked strong offensively, putting up 392 yards of total offense against Washington. Their 9.0 yards per attempt in the air was a big difference maker, but they only managed 3.7 yards per carry on the ground. When you consider that Washington was dead last in pass defense DVOA in 2023, the performance seems less impressive. They’ll take on a Detroit defense in Week 2 that is expected to be much improved from the nearly average unit last season. They gave up 304 yards to Matthew Stafford and the Rams last week, but it came on 49 passes, and Stafford was constantly under pressure even though he was getting rid of the ball quickly. Offensively, Detroit imposed their will on the ground when they didn’t look their best. A lot of steam has come in on Detroit this week, and I’ll also be backing them.

Pick: Lions -7.5

  • Ryan Rodeman

Colts vs. Packers

Before Week 1, this was a game to watch as it featured two young, up-and-coming quarterbacks, Anthony Richardson and Jordan Love. But with Love injured and Malik Lewis to start despite only being on the roster a couple of weeks, much of the luster of a promising matchup is gone. Both teams will likely feature the run, Indianapolis because Jonathan Taylor is a stud and Green Bay because Lewis has been an abysmal passer in the NFL. However, unlike the Packers, the Colts will not be stuck running a one-dimensional offense, giving Indianapolis the edge. But if the Pack can run wild on the Colts like Houston did, Green Bay could run away with it. Expect a lot of running in this game but not much scoring.

Pick: Under 40.5

  • Travis Pulver

Jets vs. Titans

On Monday night Aaron Rodgers made his full debut for the Jets. The results were underwhelming as the offense was held to 266 yards in a 13-point loss to the 49ers. The Jets’ defense was especially of concern as they gave up 401 yards, including 180 yards on the ground. Luckily for them, they don’t need to play the 49ers again in Week 2. They get the Titans. Tennessee got their season off to a rousing start with a 17-0 lead in Chicago. But three turnovers, including a pick-six and a blocked punt for a touchdown, helped the Bears pull off a 24-17 victory despite just 2.8 yards per play on offense. The Jets were a top-three defense per DVOA in 2023, and there’s reason to believe they should be comparable in 2024. Tennessee already showed they have a strong defense against Chicago. I don’t trust either of these offenses yet so I’ll play the under.

Pick: Under 41.5

  • Ryan Rodeman

49ers vs. Vikings

The 49ers looked excellent in Week 1 against the Jets. Although Christian McCaffrey could not play, the 49ers accumulated 401 yards of offense, including 180 yards on the ground, mainly from Jordan Mason. However, it sounds like McCaffrey will return for this Week 2 matchup against the Vikings. It'll only make the 49ers' offense more lethal. On the other hand, Sam Darnold and the Minnesota Vikings earned a dominant road win against the Giants. However, Darnold came to Minnesota from the 49ers. I'd imagine the Niners will be better prepared simply by knowing how Darnold prepares for games during his time in San Francisco. Plus, the Vikings' pass protection still didn't impress against the Giants and certainly won't hold off the 49ers. Let's take San Francisco -5 (-110).

Pick: 49ers -5

  • Jason Radowitz

Seahawks vs. Patriots

The Patriots shocked the NFL world with a Week 1 victory over the Bengals. New England only won the game, 16-10, allowing just one touchdown on the road. Ultimately, the Bengals shot themselves in the foot with multiple fumbles during drives that should've led to points for Cincinnati. That said, New England earned below 300 yards of offense and wasn't excellent. The Patriots just controlled the clock and wore down the Bengals. They also kept Burrow and the Bengals away from more opportunities at a comeback. Still, let's not overreact. The Patriots aren't going to be great this season with Jacoby Brissett under center. Seattle's offense has way more potential, and the defense was imposing against the Broncos, especially against the run in Week 1. Therefore, I'll back the Seahawks at -3.5 (+100).

Pick: Seahawks -3.5

  • Jason Radowitz

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Giants vs. Commanders

The New York Giants looked pitiful against the Vikings to start the season, losing 28-6 without scoring a touchdown. However, I'd expect some improvements from the Giants this week with a matchup against the Washington Commanders. The Commanders allowed Baker Mayfield to record four touchdowns and pass for nearly 300 yards of offense. Yes, even Daniel Jones can make some of those passes when there's no pressure from a pass rush. On the other hand, the Commanders got some good play from rookie quarterback Jayden Daniels. While he threw for just 184 yards, he also recorded two rushing touchdowns and ran for 88 yards. I'd expect him to run all over the Giants in Week 2. Therefore, I'll back the Over 43.5 in this one.

Pick: Over 43.5

  • Jason Radowitz

Chargers vs. Panthers

The Chargers hit the road to battle the Panthers, and we should have some windy conditions, with gusts 12-15 MPH. Another thing that blows is the Panthers, as they were absolutely trucked in New Orleans last week, falling 47-10. To make matters worse, the Panthers are now without DL Derrick Brown, their best defender, as he suffered a knee injury in New Orleans. When it rains, it pours. Head coach Jim Harbaugh got his first win in his return to the NFL last week against the visiting Las Vegas Raiders, and now he’ll get his first road win since returning. The Panthers are pathetic, and their toothless offense is unlikely to be able to solve the Bolts on D. This should be a lower-scoring game, with the Chargers pulling away in the second half to win by at least a touchdown.

Pick: Chargers -5.5

  • Daniel Dobish

Browns vs. Jaguars

These two playoff hopefuls are looking to avoid an 0-2 hole. The Browns weren’t ready for a marquee game in Week 1, as the Dallas Cowboys trounced them 33-17. To make matters worse, TE David Njoku was lost to injury, and there is another off-field issue or accusation following QB Deshaun Watson around. The drama never seems to end for this organization, and it’s a huge distraction for a team which, on paper, should be very good. The Jaguars appeared to have things under control in Week 1 at Miami, but they self-destructed in the fourth quarter, falling 20-17, although they were able to cover the spread. We’ll get some early showers in this game, persisting into the second quarter, and the slick track could mean more of a ground-based attack with some miscues. We should see a dry track, and the pass game picking up in the final 30 minutes. Look for QB Trevor Lawrence to get on track at home in a lower-scoring battle between two teams with strong defensive units.

Pick: Under 41.5

  • Daniel Dobish

Raiders vs. Ravens

The Ravens were a toe away from starting off the season with a road win in Kansas City, but alas, they fell in the contest and now find themselves needing a win in Week 2 to avoid the dreaded 0-2 start. Luckily for them they get the Raiders and what is on pace to be the largest spread of the weekend in the NFL. The Raiders come into this one after a rough loss to the Chargers. Las Vegas actually put up the first points in the game and their defense held the Chargers to nine points through the first three quarters. A turnover on downs, two fumbles and a missed field goal eventually caught up to them and the Chargers pulled away for a 22-10 win. Overall is was a decent defensive showing. The Ravens’ defense actually did a solid job slowing down the Kansas City offense, allowing just 353 yards. They should be able to slow down the Las Vegas offense that scored just 10 last week and ranked 27th last year in offensive DVOA. This game is shaping up to be a defensive battle where the under is in play.

Pick: Under 41.5

  • Ryan Rodeman

Rams vs. Cardinals

Los Angeles swept this NFC West division series last year. Kyren Williams ran for over 300 total yards in the two Rams victories. Arizona was without franchise quarterback Kyler Murray in the first meeting and Murray was playing in just his third game back from a torn ACL in the second Cardinals loss. Los Angeles will be without wide receiver Puka Nacua in this one since the young wideout was placed on IR this week. Look for the Rams to lean heavily on Williams and Cooper Kupp, who looks completely healthy once again and was targeted 21 times in last week’s OT win over Detroit.

Pick: Rams +1.5

  • Tom Stad

Steelers vs. Broncos

If last week was any indication of what to expect in this AFC matchup, the first team to reach 14 may win this one. The Steelers have yet to find the end zone this season but are 1-0 thanks to six field goals by Chris Boswell in an 18-10 win over the Falcons. Former Denver quarterback Russell Wilson won’t get the chance to take on his former team, as Steelers head coach Mike Tomlin said earlier in the week that Justin Fields will get another start. Broncos rookie quarterback Bo Nix was mediocre at best for the Broncos in a 26-20 loss to Seattle last week, throwing for just 138 yards and 2 TDs. Things weren’t any better on the ground for head coach Sean Payton’s offense as Nix led the team with just 35 yards on the ground. Look for both offenses to struggle in this one.

Pick: Under 36.5

  • Tom Stad

Bengals vs. Chiefs

Perhaps the biggest stunner of the first week was Cincinnati falling to the Patriots in their home opener 16-10. The Bengals offense looked lost without former running back Joe Mixon, now in Houston, Tee Higgins who was out due to injury, and star wide receiver Ja’marr Chase limited due to a contract dispute that caused him to miss most of the offseason. Patrick Mahomes and the Chiefs had to battle hard and were just inches (or less) from being taken to OT by the Ravens in a 27-20 season-opening victory. The Bengals are a miserable 1-8 in the first two weeks of the season since Joe Burrow took over as starting quarterback. Look for that trend to continue in Kansas City.

Pick: KC -5.5

  • Tom Stad

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