NFL Week 4 Odds, Picks & Predictions: Bills vs. Ravens (2022)

Here is an early look at our odds, picks, and predictions for the NFL Week 4 game, Bills vs. Ravens.

And check out a few of our other favorite bets for Week 4:

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

NFL Week 4 Odds, Picks & Predictions: Bills vs. Ravens

Two of the most talented quarterbacks in the league square off in this week 4 matchup. QB Lamar Jackson continues to eviscerate every defense he goes up against both in the air and on the ground, leading to a 1st place ranking in offensive DVOA for the Ravens.

The Buffalo Bills, led by QB Josh Allen, have also been excellent on offense (6th in offensive DVOA), but it has been a stout defense that has impressed the most. Dominating the Rams and Titans, as well as slowing down a potent Miami offense, shows they are not going to be intimidated by anyone. However, the strength of Bills defense is the pass rush, which can be negated by an impactful runner like Lamar Jackson.

With the possibility of wet conditions in the forecast, you have to back the more explosive running attack at home.

Ravens +3, o51

What is Betting Against the Spread?

Betting "against the spread" refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | RadioPublic | Breaker | Castbox | Pocket Casts

Whether you're new to sports betting or a betting pro, our How To Bet and Sports Betting Strategy and Advice pages are for you. You can get started with our How To Section - including How to Avoid the 7 Biggest Sports Betting Mistakes - or head to a more advanced strategy - like Thinking Like an Expert Sports Bettor - to learn more.

Try Premium for FREE in our mobile app