NFL Week 5 Odds, Picks & Predictions: Eagles vs. Cardinals (2022)

We’re here to get you ready for Week 5. Here’s a closer look at the NFL Week 5 matchup: Eagles vs. Cardinals.

Here are other Week 5 game previews:

• Giants vs. Packers
• Steelers vs. Bills
• Chargers vs. Browns
• Bears vs. Vikings
• Lions vs. Patriots
• Seahawks vs. Saints
• Dolphins vs. Jets
• Falcons vs. Buccaneers
• Titans vs. Commanders
• Texans vs. Jaguars
• 49ers vs. Panthers
• Cowboys vs. Rams
• Bengals vs. Ravens
• Raiders vs. Chiefs

And check out our best bets of the week from our analysts:

• Matthew Freedman's NFL Week 5 Early Bets and Trends
• NFL Week 5 Early Lines vs. Line Movement Predictions
• Video: NFL Week 5 Early Odds, Picks & Predictions

Prop Bet Analyzer: View top-rated props and historical prop performance by player >>

NFL Week 5 Odds, Picks & Predictions: Eagles vs. Cardinals

Don't let their pedestrian 2-2 record fool you, the Cardinals may be one of the worst teams in the NFL. Their win versus Carolina was given, not earned, and the team is going to struggle versus a stout Eagles Defense ranked second in EPA / Play and third in Total DVOA. Expect the Eagles to build an early lead for one of the NFL's premier pass-rushing units to make life hell for QB Kyler Murray.

Additionally, the Cardinals haven't covered at home in seven straight games, and HC Kliff Kingsbury has an all time 9-17 ATS record in State Farm Stadium. Back the Eagles as a trendy road pick, this number should be seven.

Eagles -5, lean u49

View 5-star bets and historical prop performance by player with our Prop Bet Analyzer >>

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