NFL Week 5 Odds, Picks & Predictions: Steelers vs. Bills (2022)

We’re here to get you ready for Week 5. Here’s a closer look at the NFL Week 5 matchup: Steelers vs. Bills.

Here are other Week 5 game previews:

• Giants vs. Packers
• Chargers vs. Browns
• Bears vs. Vikings
• Lions vs. Patriots
• Seahawks vs. Saints
• Dolphins vs. Jets
• Falcons vs. Buccaneers
• Titans vs. Commanders
• Texans vs. Jaguars
• 49ers vs. Panthers
• Cowboys vs. Rams
• Eagles vs. Cardinals
• Bengals vs. Ravens
• Raiders vs. Chiefs

And check out our best bets of the week from our analysts:

• Matthew Freedman's NFL Week 5 Early Bets and Trends
• NFL Week 5 Early Lines vs. Line Movement Predictions
• Video: NFL Week 5 Early Odds, Picks & Predictions

Prop Bet Analyzer: View top-rated props and historical prop performance by player >>

NFL Week 5 Odds, Picks & Predictions: Steelers vs. Bills

Kenny Pickett and the Steelers head to Buffalo as a heavy underdog. The Steelers are coming off a 4th quarter collapse to the Jets while the Bills are coming off a second-half comeback to beat the Ravens.

The Steelers are big underdogs for good reason. The Bills have given up the second-fewest yards, the third-most takeaways, and to top it off, they have only given up 7 points in the second half all season.

For the Steelers, Kenny Pickett needs to revamp their dull offense as they have put up the third-fewest yards per game of any team and a bottom 5 team in passing yards per game. They are averaging 10 points less per game compared to the Bills, which is a ton, but in this game, 10 points will do just fine.

Lean Steelers +14, u46.5

View 5-star bets and historical prop performance by player with our Prop Bet Analyzer >>

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