NFL Week 6 Early Odds, Picks & Predictions: Cowboys vs. Eagles (2022)

We’re here to get you ready for Week 6. You can check out all of our early Week 5 NFL content below, including our early picks and predictions for the week ahead. And here’s a closer look at the NFL Week 6 matchup: Cowboys vs. Eagles.

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NFL Week 6 Early Odds, Picks & Predictions: Cowboys vs. Eagles

Dallas Cowboys and Philadelphia Eagles Under 42.5 (-110)

On the NFC side, this will be the game you’ll want to keep your eye on. It’s no secret that the Eagles and Cowboys do not like each other, and this will be one of those dogfight types of games. The over has hit in the last three matchups, but this will be the first time both teams are within the top 10 in scoring defense in that span.

The Cowboys could see Dan Prescott back behind center as he recovers from the thumb injury that had him out of the last four games. He says he can now grip the football and the game’s adrenaline with help. But how much will he be able to do?

We’ve seen Jalen Hurts emerge as a superstar, and the Dallas defense hasn’t seen a quarterback this season that can pass and run well. Still, they’ve also seen some of the best talents in the league, including three quarterbacks recently playing in Super Bowls (Tom Brady, Matthew Stafford and Joe Burrow).


What is Betting Against the Spread?

Betting “against the spread” refers to the act of choosing the winning team based on a numeric handicap placed on the team that oddsmakers believe is superior, rather than picking the outright winner. For example, if the Rams face the Bengals, and oddsmakers set the spread at Rams -3.5, you would need Los Angeles to win by 4 or more points in order to cash your Rams bet.

What is an Over/Under Bet?

Over/Under is a wager based on how many points you think will be scored in a specific game. Oddsmakers set the total, and bettors decide whether the final score will be higher or lower than that number. If an Over/Under is set at 44.5 points and you bet Over, you will need the combined score of both teams to be 45 points or higher to win your bet.

What is a Moneyline Bet?

A moneyline bet involves choosing which team you believe will win a specific matchup. The moneyline favorite carries a minus designation, like -130. This means that you need to wager $130 to earn a $100 profit. Conversely, the underdog carries a plus designation, like +110. This means that you win $110 in profit on a $100 bet.

View 5-star bets and historical prop performance by player with our Prop Bet Analyzer >>

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