NFL Week 6 Early Odds, Picks & Predictions: Jaguars vs. Colts (2022)

Last week, I suggested picking up the Chargers at -125 for Week 5. They’ve increased their odds to -135 going up against the Cleveland Browns on the road.

There’s also plenty of value a week in advance. If you can do the proper research and break down how each game on Sunday will go, you can find some excellent lines heading into Week 6. Let’s take a look at a game I’m betting early: Jaguars vs. Colts.

(Odds courtesy DraftKings Sportsbook)

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NFL Week 6 Early Odds, Picks & Predictions: Jaguars vs. Colts

Jacksonville Jaguars vs. Indianapolis Colts

The Colts knocked off the Kansas City Chiefs a couple of weeks ago. But that’s their only win. On Thursday Night, they’ll take on the Denver Broncos without Jonathan Taylor in the lineup.

Who knows if he’ll even be ready for the following week against the Jaguars.

In their first meeting this year, the Jags already defeated the Colts, 24-0. Things could get ugly if Indianapolis doesn’t have Taylor in that second game.

Meanwhile, the Jaguars are seven-point favorites against the Houston Texans, and with a win, more money will start to pour on the Jaguars, even on the road, against the Colts. Grab them now.

Bet: Jaguars ML (+115)

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