NFL Week 6 Odds, Picks & Predictions: Cardinals vs. Seahawks (2022)

We’re here to get you ready for Week 6. Here’s a closer look at the NFL Week 6 matchup: Cardinals vs. Seahawks.

Prop Bet Analyzer: View top-rated props and historical prop performance by player >>

NFL Week 6 Odds, Picks & Predictions: Cardinals vs. Seahawks

The Seattle Seahawks are underdogs this week at home against the Arizona Cardinals.

The Seahawks’ offense is starting to click. Geno Smith is leading the league with a 75.2% completion percentage. This week against New Orleans, he connected with Tyler Lockett and D.K. Metcalf for a combined 10 catches, 192 yards, and 3 touchdowns on 14 targets. The season-ending injury to Rashaad Penny is a blow to the run game, but Kenneth Walker III filled in after Penny left the game and rushed the ball eight times for 88 yards and a touchdown.

The Cardinals are coming to Seattle after a tough loss to the first-place Philadelphia Eagles. Losing to the 5-0 Eagles isn’t an indictment especially considering they came within a missed field goal away from forcing overtime. However, the ankle injury to James Conner may prove to be costly to the Cardinals if he misses much time. Per Statmuse, since 2021, Conner only trails Austin Ekeler, Cooper Kupp, and Jonathan Taylor in touchdowns. That puts him ahead of guys like Travis Kelce, Davante Adams, and Tyreek Hill. If Conner misses this game, that is a big part of their offense missing, leaving them with the tough task of keeping up with the surprisingly good Seattle Seahawks’ offense.

Pick: The Seattle Seahawks (+120)

View 5-star bets and historical prop performance by player with our Prop Bet Analyzer >>

Subscribe: Apple Podcasts | Spotify | Google Podcasts | Stitcher | RadioPublic | Breaker | Castbox | Pocket Casts

Whether you’re new to sports betting or a betting pro, our How To Bet and Sports Betting Strategy and Advice pages are for you. You can get started with our How To Section — including How to Avoid the 7 Biggest Sports Betting Mistakes â€” or head to a more advanced strategy — like Thinking Like an Expert Sports Bettor â€” to learn more.

Try Premium for FREE in our mobile app