NFL Week 6 Picks & Predictions: Bills vs. Chiefs (2022)
We’re here to get you ready for Week 6. Here’s a closer look at the NFL Week 6 matchup: Bills vs. Chiefs.
And check out our other NFL Week 6 game previews and picks:
- 49ers vs. Falcons
- Patriots vs. Browns
- Jets vs. Packers
- Jaguars vs. Colts
- Vikings vs. Dolphins
- Bengals vs. Saints
- Ravens vs. Giants
- Buccaneers vs. Steelers
- Panthers vs. Rams
- Cardinals vs. Seahawks
- Cowboys vs. Eagles
- Broncos vs. Chargers
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NFL Week 6 Picks & Predictions: Bills vs. Chiefs
The Bills visit the Chiefs in a rematch of one of the greatest games ever played, and this game will likely be integral in determining the top seed in the AFC. The Bills just throttled Pittsburgh, and their impressive start to the season coincides with an opportunity to overtake their proverbial 'little brother' in the AFC hierarchy.
Buffalo is the rightful Super Bowl favorite, and Josh Allen is likely the MVP, but be hesitant in backing them as a favorite in Arrowhead Stadium. In his career, Chiefs QB Patrick Mahomes is 7-0-1 ATS as an underdog, and is 3-1 SU versus Josh Allen's Bills. This is likely a better game to live-bet either side, but I'll side with the Chiefs in what projects to be a thrilling game.
View 5-star bets and historical prop performance by player with our Prop Bet Analyzer >>
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