Premier League Matchday 22 Odds, Picks & Predictions (2023)

The English Premier League returns with a vengeance for matchday 22 after taking the previous weekend off to accommodate Round 4 of the FA Cup. This weekend is packed with games, and Manchester United’s match against Leeds on the following Thursday adds an extra bonus.

With the transfer window officially closed, the teams are ready for the final stretch, and there is a lot to play for at both ends of the Premier League table.

Here are two games this weekend that I’m dialed in on.

(Odds courtesy of DraftKings Sportsbook)

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Premier League Matchday 22 Preview & Best Bets (2023)

Everton (+700) vs. Arsenal (-250)

Arsenal, who are currently atop the Premier League and are heavy favorites to win the championship, will go to Goodison Park with memories of their dramatic loss there last season still in their minds.

Sean Dyche, the former Burnley manager, will look to leave his mark on this team as he works to strengthen the Toffees’ defense as they turn to him to try to save their season.

Despite having their work cut out for them, Arsenal will have their best chance to turn things around at Goodison Park, where they haven’t won since October 2017. They will probably get into a low-scoring battle, so it won’t be simple, but they should figure out a way to finish the task.

Pick: Arsenal (-250)


Tottenham (+340) vs. Manchester City (-135)

The weekend comes to an end with this monumental match between Tottenham and Manchester City in North London. It will present an interesting dilemma for the Spurs because, while any outcome would help Arsenal, they still need to find a method to gain ground in the race for the top four.

A few weeks ago, these clubs played in a match, as the Spurs quickly took a 2-0 lead before City came back and won 4-2 in the end. The best course of action in this situation is to not overthink it and back City to win with a goal from their Norwegian star Erling Haaland.

Pick: Manchester City (-135)


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