Premier League Matchday 35 Odds, Picks & Prediction (2024)

Matchday 35 in the Premier League got underway Tuesday, as Arsenal spanked Chelsea 5-0 at Emirates Stadium. They're up to 77 points on the year, which currently tops the table.

We have another five games over the next two days, and I'll be breaking down three of them from a betting perspective.

Here are my three favorite bets in the EPL this week.

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Premier League Matchday 35 Preview & Best Bets

(Odds courtesy of DraftKings Sportsbook)

Everton (+650) vs. Liverpool (-245), DRAW (+425) | O/U 3.5 (+140/-170)

The historic Merseyside Derby is scheduled for Wednesday, and both teams desperately need points as we approach the end of the 2023-2024 campaign. Everton is currently 16th in the table (30 points), while Liverpool is second (74 points). Kickoff is scheduled for 3:00 p.m. ET from Goodison Park in Liverpool, England.

Even if you give the Toffees their six points back from the penalty earlier in the year, that would still put them in just 14th place. This has been a rough season for Everton, and it's mainly been their offense that's held them back. Sean Dyche's squad has netted just 34 goals, which is the second-worst in the PL. 

You never want to be lacking offensive production, especially when Liverpool pops up on the schedule. The Reds have been excellent on offense this term, amassing 71 goals, which is third in the league. They're coming off an easy 3-1 road win over Fulham, where Jurgen Klopp rested several of his big stars. Mohamed Salah, Darwin Nunez and Alexis Mac Allister each came off the bench late, so they should be fresh for the upcoming derby. This motivated Liverpool side should cruise to another multi-goal victory with their best forwards having a full tank of gas.

Bet: Liverpool -1.5 (+105)


Manchester United (-300) vs. Sheffield United (+700), DRAW (+500) | O/U 3.5 (-105/-120)

Erik ten Hag's Red Devils punched their ticket to the FA Cup Final this past weekend, slipping past Coventry City in a 3-3 match that ended in penalties (United advanced 4-2 on penalties). They'll resume PL action on Wednesday, where they host last-place Sheffield United (16 points). This one gets underway at 3:00 p.m. ET from Old Trafford in Manchester, England. 

I'm always looking for a way to fade Sheffield, and I'll specifically be betting against their defense this week. The Blades have conceded 88 goals over 33 matches, which equates to an average of 2.7 GA/G. The two sides played back in October, and Manchester United escaped with a 2-1 victory. However, United's offense was in shambles back then, and they've started to find their footing as the season continues. I'll lock in the Red Devils to score at least three times against the Blades on Wednesday. 

Over their last seven matches, Manchester United has averaged 2.1 goals per match. They've scored at least twice in six of those games and reached a third goal on three occasions. With Sheffield bringing in a historically bad defense, I think Manchester United should be able to score three goals. They've done so in three of the last five head-to-head meetings between the two clubs. 

Bet: Manchester United Over 2.5 Team Total (-110)


Brighton (+600) vs. Manchester City (-235), DRAW (+400) | O/U 3.5 (+130/-160)

The midweek action wraps up on Thursday with a standalone match between Brighton & Hove Albion and Manchester City. The Seagulls currently reside in 10th in the table (44 points), while the visitors enter this contest sitting in third (73 points). Kickoff is set for 3:00 p.m. ET from American Express Stadium in Falmer. England. 

Pep Guardiola and his Citizens have been a busy bunch recently, managing both UCL and FA Cup schedules. However, they exited the European stage with a loss to Real Madrid, and City won't have to worry about the FA Cup Final for another month (May 25 vs. Manchester United). They'll focus their attention back to the PL, where they're looking to capture their fourth-straight league title. 

I think City takes another step toward the four-peat, collecting three points on the road against Brighton. I also expect to see at least three goals, and this head-to-head series has featured at least three goals in eight of the last 10 meetings. While we're touching on the history of this series, it's worth noting that City is 12-1-1 in the last 14 head-to-head matches.

Aside from losing to Madrid in penalties in the Champions League, City appears to be back in championship form. They're 3-0-0 in their last three PL matches, out-scoring their opposition 13-4 over the three-game span. Each of those matches has seen City score at least three goals by themselves. Look for them to stay hot in Falmer on Thursday, securing a win in a higher-scoring affair. 

Bet: Manchester City To Win & Over 2.5 Goals (-110)


Make sure to check out our other best bets for Wednesday:

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